Currently used to treat erectile dysfunction (ED) prescription drugs most commonly there are three, namely Viagra, Cialis and Levitra. They all belong to 5 - phosphodiesterase inhibitor, in elderly men in particular, a broad application. Because these patients are often taking other drugs, these drugs with anti-ED drug interaction may exist, older male friends this must not be taken lightly.
And nitroglycerin with the use of: low blood pressure
Required taking nitrates such as nitroglycerin-type drugs (such as nitroglycerin) or α-receptor blockers (such as doxazosin, prazosin, terazosin, tamsulosin and alfuzosin, etc. ) used with caution in patients who required anti-ED drugs.
This is because Viagra, Cialis and Levitra have the role of diastolic blood vessels, and nitroglycerin and prazosin also has the role of the expansion of blood vessels, joint use, this role will be magnified, so that blood pressure decreased significantly and increase the risk of heart attack or stroke. If you are the application of such current antihypertensive agents, anti-ED drug in the application before, please consult a physician, he may suggest you adjust the dose.
And ketoconazole with the use of: poisoning
Ketoconazole is a common antifungal agents, patients taking anti-ED drug and ketoconazole, may lead to an increase in anti-ED probability of adverse drug reactions. Have the same effect of drugs, including clarithromycin, cyclosporine, itraconazole, and ritonavir.
Human metabolism of drugs can not do without the help of enzymes, and CYP3A4 are the most important drug-metabolizing enzymes. Including anti-ED drug, including the majority of drug metabolism through CYP3A4, while these drugs can inhibit CYP3A4 precisely the activity, and anti-ED drugs at the same time using it, probably the former increases the concentration in the blood, increasing the potential toxicity of drugs. With this role is more than drugs, certain beverages, such as grapefruit juice may inhibit CYP3A4 activity, anti-ED drugs patients must want their distance.
And dexamethasone with the use of: lower efficacy
Carbamazepine, dexamethasone, rifamycin CYP3A4 activity is to enhance the equality of the drugs, can reduce the role of anti-ED drugs. Of course, there is nothing so dangerous, but will anti-ED drugs ineffective. If the CYP3A4 activity significantly, such as patients taking rifampicin, even if the application of anti-ED drugs, the highest recommended dose is invalid.
There are lot of medicines may be associated with anti-ED drug interactions, and therefore anti-ED drugs issued by a physician should pay attention to you are taking other drugs, whether or not all belong to the above categories. If you are in the application of anti-ED drug application after the start or stop the other drugs, please pay attention to anti-ED drugs would therefore be affected.
And nitroglycerin with the use of: low blood pressure
Required taking nitrates such as nitroglycerin-type drugs (such as nitroglycerin) or α-receptor blockers (such as doxazosin, prazosin, terazosin, tamsulosin and alfuzosin, etc. ) used with caution in patients who required anti-ED drugs.
This is because Viagra, Cialis and Levitra have the role of diastolic blood vessels, and nitroglycerin and prazosin also has the role of the expansion of blood vessels, joint use, this role will be magnified, so that blood pressure decreased significantly and increase the risk of heart attack or stroke. If you are the application of such current antihypertensive agents, anti-ED drug in the application before, please consult a physician, he may suggest you adjust the dose.
And ketoconazole with the use of: poisoning
Ketoconazole is a common antifungal agents, patients taking anti-ED drug and ketoconazole, may lead to an increase in anti-ED probability of adverse drug reactions. Have the same effect of drugs, including clarithromycin, cyclosporine, itraconazole, and ritonavir.
Human metabolism of drugs can not do without the help of enzymes, and CYP3A4 are the most important drug-metabolizing enzymes. Including anti-ED drug, including the majority of drug metabolism through CYP3A4, while these drugs can inhibit CYP3A4 precisely the activity, and anti-ED drugs at the same time using it, probably the former increases the concentration in the blood, increasing the potential toxicity of drugs. With this role is more than drugs, certain beverages, such as grapefruit juice may inhibit CYP3A4 activity, anti-ED drugs patients must want their distance.
And dexamethasone with the use of: lower efficacy
Carbamazepine, dexamethasone, rifamycin CYP3A4 activity is to enhance the equality of the drugs, can reduce the role of anti-ED drugs. Of course, there is nothing so dangerous, but will anti-ED drugs ineffective. If the CYP3A4 activity significantly, such as patients taking rifampicin, even if the application of anti-ED drugs, the highest recommended dose is invalid.
There are lot of medicines may be associated with anti-ED drug interactions, and therefore anti-ED drugs issued by a physician should pay attention to you are taking other drugs, whether or not all belong to the above categories. If you are in the application of anti-ED drug application after the start or stop the other drugs, please pay attention to anti-ED drugs would therefore be affected.
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