The medical profession are aware, pre-menopausal women in the incidence of coronary heart disease should be significantly lower than that of men the same age, but after menopause the incidence and mortality rates are significantly higher, and even the same men with their peers. Although in the past have found that this pre-menopausal women with estrogen-high, and the effects of estrogen on coronary vascular smooth muscle has direct expansion effects. But the latest findings provide a new understanding, that is, pre-menopausal women, through menstruation excessive reduction of body iron, is that they can maintain a healthy circulatory system important reasons.
Regular blood donors with low heart disease mortality
"Journal of the American Medical Association" published an article last 6 years to complete reports. Of their research for the age of 43 ~ 87-year-old males and females, a total of 1277 people. These people are suffering from limb arterial disease because of arterial stenosis of the restrictions, the limbs do not receive adequate blood supply.Necessary for treatment, research subjects have 636 people in 6 months time interval, quantitative intravenous bloodletting, with a view to reducing the viscosity of blood; while another 641 people are not bleeding, but the control. All patients by the host hospital, age, smoking status, diagnosis of diabetes status, low-density and high density lipoprotein cholesterol content ratio, and serum ferritin concentration also make a further classification. Observation of the first indicators are the total mortality in each group, while the secondary indicators are because of non-fatal myocardial infarction and stroke caused by the circumstances of the death.
At the end of the study, two groups in mortality, heart attack or because of the problems caused by other reasons, and did not appear significantly different, but only the analysis of the age of 43 ~ 61-year-old patients, they found that iron deficiency (bleeding) Group very few died of fatal heart attacks and stroke, as well as from other causes of death.
Although iron is indispensable for the human body and essential nutrients, but new research has shown that if the body iron content more than the limits required, it may be caused by vascular endothelial cell layer damage, increased atherosclerosis and heart attack opportunities, in heart disease especially the early stages.
The following study illustrates the problem:
Researchers per kg body weight dose of 0.7mg to 10 healthy volunteers were injected a lot of iron, and observed using ultrasound images of arterial wall function, has found that negative impact.
Malondialdehyde oxidation are the chemical markers, the application of excessive amounts of iron, may cause blood MDA content increased, indicating the role of the human body have a damaging role of oxygen free radicals enhanced, when the normal function of endothelial cells play will be inhibition.
As a separate study, researchers are also monitoring the 10 smokers who had reduced serum iron concentration effect and found that low serum ferritin endothelial cells can function returned to normal.
The above description, iron excess can be active in the production of oxygen free radicals, thereby enhancing the role of arterial damage. In addition, the release of vascular endothelial cell layer called "nitric oxide" of chemical substances, it has to help relax blood vessels to maintain the role of the state. Containing excessive iron hinder the role of nitric oxide exert, or narrow the blood vessel was switched off. More than cardiovascular disease may become the causes of elevated risk. Pre-menopausal women because of the laws of each month from menstruation to remove excess iron, so the chances of heart attack is relatively small.
It is obvious that the treatment of iron excessive bleeding when the vascular function to improve the situation, with conventional blood donation occurs when the situation is the same, which, experts have the following recommendations:
More research is completed before the people do not recommend trying to go through the blood to reduce the body's iron storage, because by regulating diet and the use of drugs can achieve the same objective of reducing iron.
According to the latest research reports, through the blood to reduce the body iron store in order to maintain a healthy circulatory system method does not fit in the elderly. Since, the harmful effects of excessive iron may be lasting in nature, so to obtain benefits through the reduction of iron, it should be early and continuous manner to reduce the iron treatment. Only this way can we make to keep blood vessels healthy late into life.
Age over 40 years old, and have other heart disease risk factors, such as hypertension or diabetes should regularly check the iron content of serum.
For the elderly, high-iron diet will increase the risk of myocardial infarction, which contain a large number of heme iron diet is mainly meat and meat products, so the elderly should not be eating too much meat.
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